Research Article
Synthesis and Antibacterial, Antioxidant, and Molecular Docking Analysis of Some Novel Quinoline Derivatives
Table 1
The inhibition zone of the synthetic compound in mm (mean ± SD).
| | Bacterial strains | Conc. (μg/mL) | Compounds | | 4 | 5 | 6 | 7 | 8 | 11 | 14 | 15 | 16 | 17 | Ciprofloxacin |
| | E. coli | 300 | 6.33 ± 0.44 | NA | NA | NA | 9.00 ± 0.55 | 7.33 ± 0.66 | NA | NA | 8.00 ± 0.67 | NA | 19.0 ± 0.67 | | 500 | 6.67 ± 0.89 | NA | NA | NA | 11.33 ± 1.11 | 11.0 ± 1.33 | NA | NA | 9.33 ± 0.89 | NA | 21.0 ± 0.55 | | B. subtilis | 300 | 7.0 ± 0.67 | NA | 7.0 ± 0.67 | 7.00 ± 0.67 | 6.67 ± 0.89 | NA | 6.67 ± 0.44 | NA | 6.33 ± 0.44 | 6.33 ± 0.44 | 30.0 ± 0.67 | | 500 | 7.67 ± 0.44 | NA | 7.67 ± 0.44 | 7.33 ± 0.44 | 7.00 ± 0.67 | NA | 7.33 ± 0.44 | NA | 7.33 ± 0.44 | 7.33 ± 0.44 | 33.0 ± 0.67 | | S. aureus | 300 | 6.33 ± 0.44 | 6.00 ±0.00 | NA | NA | 6.00 ± 0.00 | NA | NA | 6.00 ± 0.44 | NA | NA | 9.0 ± 0.67 | | 500 | 7.0 ± 0.67 | 6.33 ± 0.44 | 6.00 ± 0.00 | NA | 6.33 ± 0.44 | NA | NA | 6.67 ± 0.44 | NA | NA | 11.0 ± 0.67 | | P. aeruginosa | 300 | 7.0 ± 0.67 | 7.67 ± 0.44 | 8.0 ± 0.67 | 6.33 ± 0.44 | 7.00 ± 0.00 | 6.00 ±0.00 | 6.33 ± 0.44 | 8.33 ± 0.44 | NA | NA | 7.00 ± 0.00 | | 500 | 9.0 ± 0.67 | 9.33 ± 0.44 | 9.67 ± 1.11 | 6.33 ± 0.44 | 8.00 ± 0.67 | 6.33 ± 0.44 | 7.33 ± 0.44 | 10.00.44 | NA | NA | 8.33 ± 0.44 |
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NA: no inhibition zone; results are expressed as M±SD of triplicates.
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