Journal of Chemistry / 2020 / Article / Tab 1

Research Article

Synthesis of Phenols via Metal-Free Hydroxylation of Aryl Boronic Acids with Aqueous TBHP

Table 1

Solvent study: hydroxylation of phenylboronic acida.

EntrySolventTemp. (°C)Time (h)Yield (%)b,c

3THF : H2O25122
4CH3CN : H2O25310
5DMF : H2O703>5d
6THF : H2O50325

aReaction conditions: phenylboronic acid (1 mmol), aqueous TBHP (1 mmol), Cs2CO3 (0.5 mmol), and solvent stirred at designated temperature and time; bisolated yield; cproducts were characterized by MP, FTIR, and 1H- and 13C-NMR; dtraces of the product when CH3CN and pyridine solvents were used.

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.