Research Article
Synthesis of Phenols via Metal-Free Hydroxylation of Aryl Boronic Acids with Aqueous TBHP
Table 2
Optimization of hydroxylation parametersa.
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aReaction conditions: phenylboronic acid (1 mmol), aqueous TBHP base, and water (1 mL) stirred at designated temperature and time; bIsolated yield after workup; cProducts were characterized by MP, FTIR, and 1H- and 13C-NMR; dTHF was added to mix reactants. eYield after 2 hours. |