Using Topomer Comparative Molecular Field Analysis to Elucidate Activity Differences of Aminomethylenethiophene Derivatives as Lysyl Oxidase Inhibitors: Implications for Rational Design of Antimetastatic Agents for Cancer Therapy

Table 2

Statistical results of the topomer CoMFA model.

Statistical parameters
F values	62.193
ONC	5
SEE	0.180
r^2	0.912
q^2	0.540

F: significant test value. ONC: optimal number of components (LVs). SEE: standard error of estimate. r²: non-cross-validation correlation coefficient. q²: leave-one-out cross-validation correlation coefficient.