Research Article
Synthesis and Antimicrobial Resistant Modulatory Activity of 2,4-Dinitrophenylhydrazone Derivatives as Agents against Some ESKAPE Human Pathogens
Table 3
Resistant modulatory activity of the compounds against the panel of organisms.
| | Test organisms | Minimum inhibitory concentrations (µM) of the phenylhydrazones | | BP1 | BA2 | MHB3 | VL4 | SA5 | DHB6 | CPR | FLZ |
| | Staphylococcus aureus (+) | >138 | 87.3 | 165 | >150 | >165 | >157 | 4.72 | — | | Streptococcus pneumoniae (+) | 1.078 | 1.36 | 1.29 | 1.176 | 1.29 | 1.23 | 2.36 | — | | Escherichia coli (−) | >138 | >175 | >165 | >150 | >165 | >157 | 4.72 | — | | Pseudomonas aeruginosa (−) | >17.2 | 87.3 | 82.7 | 75.2 | 2.58 | 39.3 | 2.36 | — | | Klebsiella pneumoniae (−) | 1.078 | 5.46 | 1.29 | 1.176 | 1.29 | 1.23 | 2.36 | — | | Candida albicans | 2.156 | 273 | 5.109 | 1.176 | 1.29 | 1.23 | — | 327 |
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