Research Article
Synthesis, Spectroscopic Characterization, Structural Studies, and In Vitro Antitumor Activities of Pyridine-3-carbaldehyde Thiosemicarbazone Derivatives
Table 4
Selectivity of the cytotoxicity of the pyridine-3-carbaldehyde thiosemicarbazone derivatives (1–8) to tumor cells, as compared with 3T3 non-tumor cells.
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aThe selectivity index is the ratio of the IC50 values of the compounds on 3T3 cells to those in the tumor cell lines. NC = unable to calculate. b5-Fluorouracile. |