Research Article

Synthesis, Characterization, and DNA-Binding Kinetics of New Pd(II) and Pt(II) Thiosemicarbazone Complexes: Spectral, Structural, and Anticancer Evaluation

Table 3

The IC50 values for ligands and complexes C1–C4.

Complex (µM)
C1C2C3C4Ligands

Caco-214.71 ± 0.01643.08 ± 0.00117.52 ± 0.00531.14 ± 0.002>100 (L1–L4)
MCF-71.973 ± 0.04859.56 ± 0.01012.52 ± 0.01170.09 ± 0.006>100 (L1–L4)
HeLa16.65 ± 0.05172.25 ± 0.00319.2 ± 0.00346.25 ± 0.011>100 (L1–L4)
HepG214.64 ± 0.03794.34 ± 0.00329 ± 0.00348.03 ± 0.006>100 (L1–L4)
PC-314.05 ± 0.042>1006.98 ± 0.00812.63 ± 0.036>100 (L1–L4)