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Journal of Chemistry
/
2020
/
Article
/
Tab 2
/
Research Article
Metal-free Catalyzed One-Pot Multicomponent Synthesis of (E)-3-(2-((5-(Benzylideneamino)-1,3,4-thiadiazol-2-yl)thio) Acetyl)-2
H
-chromen-2-one Derivatives and Their Biological Evaluation
Table 2
Antimicrobial activity data of compounds from
4a-h
.
Compound
Concentration (
μ
g/ml)
Zone of inhibition (in mm)
Gram-positive
Gram-negative
Fungal strain
B. subtilis
S. aureus
P. aeruginosa
E. coli
C. abicans
A. niger
4a
100
24
25
23
26
24
21
b
100
24
18
21
23
21
19
c
100
25
29
24
28
24
21
d
100
21
24
23
25
23
20
e
100
25
29
26
29
23
21
f
100
26
28
25
28
25
22
g
100
21
24
24
26
21
19
h
100
25
29
24
27
23
21
Ciprofloxcin
50
26
28
24
28
—
—
Miconazole
50
—
—
—
—
25
25