Synthesis of Novel Diclofenac Hydrazones: Molecular Docking, Anti-Inflammatory, Analgesic, and Ulcerogenic Activity

Table 3

Analgesic activity of compounds by acetic acid-induced.

Treatments (n = 6)	Dose (mg/kg)	Number of writhing in 20 min.	% inhibition
Control (acetic acid)		34.16 ± 1.41
Diclofenac	10	8.00 ± 0.57	76.58
2	15.47	24.83 ± 0.79	27.31
3	15.47	8.16 ± 0.83	76.09
7	15.47	14.83 ± 1.01	56.85
8	16	8.16 ± 0.47	76.09
11	16	10.33 ± 0.80	69.75
13	14.5	8.03 ± 0.42	76.60

All values represent mean ± SEM. , followed by Student’s t-test.