3D-QSAR Study of the Chalcone Derivatives as Anticancer Agents

Table 1

Chemical structures and anticancer activities of chalcone derivatives.

	N°	Structure	pIC50
A	1	2-Cl	5.89
	2	4-Cl	5.65
	3	2-Br	5.77
	4	3-Br	5.80
	5	4-Br	5.65
	6	2-CH3	5.72
	7	3-CH3	5.84
	8	4-CH3	5.77
	9	3-OCH3	5.43
	10	4-OCH3	5.31
	11	3,5-(Cl)2	5.78
	12	3,5-(CH3)2	5.80
	13	2-Cl	6.00
B	14	3-Cl	6.13
	15	4-Cl	5.70
	16	2-CH3	6.02
	1	3-CH3	6.22
	18	4-CH3	5.70
	19	3,4-(CH3)2	5.91

Test.