Research Article
Synthesis, Characterization, and In Vitro Cytotoxicity of Platinum(II) Complexes Bearing Chiral Tetradentate Salicylaldimine Ligands
Table 2
The cytotoxicity of chiral Pt(II) complexes in vitro.
| Complex | IC50 (µM) | KB | MCF-7 |
| 1R | 12.29 | 10.08 | 1S | 11.26 | 7.15 | 2R | 29.04 | 27.80 | 2S | 22.43 | 8.97 | 3R | 22.26 | 9,27 | 3S | 21.22 | 8.12 | 4R | 30.71 | 29.01 | 4S | 13.32 | 10.01 | 5R | 13.91 | 15.58 | 5S | 10.71 | 7.51 | 6R | 10.92 | 7.18 | 6S | 10.61 | 5.72 | Ellipticine | 1.22 | 2.07 |
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