Research Article

Lysine Reacts with Cholesterol Hydroperoxide to Form Secosterol Aldehydes and Lysine-Secosterol Aldehyde Adducts

Scheme 2

Postulated reaction of secosterol aldehyde 2 with an amine to form amide adduct 10 via carbinolamine 7, Schiff’s base 8, and peroxide adduct 9. The expected masses of the protonated molecular ions are given in brackets, when RNH2 is from lysine.