Biological Removal and Fate Assessment of Diclofenac Using Bacillus subtilis and Brevibacillus laterosporus Strains and Ecotoxicological Effects of Diclofenac and 4′-Hydroxy-diclofenac

Table 1

Diclofenac transformation products reported in the literature.

Transformation products	Formula	[M + H]^+ (m/z theoretical)	Reference
2,6-Dichloro-N-(phenyl) aniline	C12H9Cl2N	238.0185	[39]
1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one	C₁₄H₉Cl₂NO	278.0134	[39]
5-Hydroxydiclofenac quinone imine	C14H9Cl2NO3	310.0032	[40]
4′-Hydroxy-diclofenac	C14H11Cl2NO3	312.0189	[41]
5-Hydroxy-diclofenac	C14H11Cl2NO3	312.0189	[41]
1-O-[2-[(2′,6′-dichlorophenyl)amino]phenyl acetyl]-b-D-glucopyranuronic acid	C20H19Cl2NO8	472.0560	[6]