Research Article

A Rapid and Sensitive UHPLC-MS/MS Method for Determination of 2, 3, 8-Trimethylellagic, a Potent Active Compound from Sanguisorba officinalis L., and Its Application in the Pharmacokinetic Study within Thrombocytopenia Rats

Table 4

Stability of TMEA under different storage condition (RSD%, n = 6).

Concentration (ng/mL)Short-term (12 h, 25°C)Plasma sample (24 h, 4°C)Long-term (30 d, −80°C)Three freeze-thaw cycles (−80°C)

1.00−8.55−1.270.28−7.34
10.00−7.262.980.60−2.58
100.001.951.08−4.54−6.57