Research Article
A Rapid and Sensitive UHPLC-MS/MS Method for Determination of 2, 3, 8-Trimethylellagic, a Potent Active Compound from Sanguisorba officinalis L., and Its Application in the Pharmacokinetic Study within Thrombocytopenia Rats
Table 5
Pharmacokinetic parameter of TMEA in rat after intragastric administration of four groups (n = 6).
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Abbreviations: NG, normal group; TG, TMEA group; TMG, TMEA-DMAG group; TOG, TMEA-DOMA group; AUC0 − t, area under the concentration–time curve from 0 to 72 h; AUC0 − ∞, area under the concentration–time curve from 0 to time infinite; MRT, mean residence time; t1/2, half-life of elimination; Tmax, time to achieve maximum concentration; Vz/F, volume of distribution; CL/F, clearance; Cmax, maximum value of concentration; , significant compared with NG, , compared with TG. |