Research Article
Synthesis of N-Methylmorpholinium Derivatives Possessing a 1,3,4-Oxadiazole Core as Feasible Antibacterial Agents against Plant Bacterial Diseases
Table 1
In vitro antibacterial effects of compounds 3a–3o against Xoo and Xac.
| Compd. | Xoo | Xac | Regression equation | R2 | EC50 (μg/mL) | Regression equation | R2 | EC50 (μg/mL) |
| 3a | y = 7.381x − 3.59 | 0.88 | 14.56 ± 1.03 | y = 1.281x + 3.60 | 0.97 | 12.41 ± 0.57 | 3b | y = 1.632x + 3.78 | 0.95 | 5.65 ± 0.88 | y = 1.300x + 4.38 | 0.95 | 2.99 ± 0.26 | 3c | y = 6.824x + 3.43 | 0.84 | 1.70 ± 0.01 | y = 4.201x + 4.13 | 0.87 | 1.61 ± 0.06 | 3d | y = 4.435x + 1.40 | 0.84 | 6.50 ± 0.30 | y = 1.183x + 4.01 | 0.98 | 6.98 ± 1.33 | 3e | y = 4.424x + 3.77 | 0.91 | 1.90 ± 0.10 | y = 2.481x + 3.87 | 0.92 | 2.86 ± 0.17 | 3f | y = 7.873x + 3.00 | 0.98 | 1.80 ± 0.14 | y = 2.881x + 4.40 | 0.95 | 1.61 ± 0.10 | 3g | y = 13.262x − 8.20 | 0.98 | 9.90 ± 0.18 | y = 2.972x + 2.26 | 0.92 | 8.36 ± 0.44 | 3h | y = 9.761x + 0.11 | 0.97 | 3.17 ± 0.42 | y = 3.600x + 3.09 | 0.95 | 3.39 ± 0.14 | 3i | y = 10.972x + 0.12 | 0.95 | 2.80 ± 0.24 | y = 6.021x + 5.26 | 0.83 | 0.90 ± 0.01 | 3j | y = 2.661x + 2.47 | 0.87 | 8.90 ± 0.81 | y = 4.173x + 0.47 | 0.92 | 12.24 ± 0.42 | 3k | y = 4.711x + 2.58 | 0.95 | 3.27 ± 0.34 | y = 0.731x + 4.39 | 0.99 | 6.92 ± 0.93 | 3l | y = 6.352x + 4.07 | 0.96 | 1.40 ± 0.06 | y = 6.572x + 3.94 | 0.97 | 1.45 ± 0.04 | 3m | y = 2.632x + 0.62 | 0.94 | 45.98 ± 4.70 | y = 1.200x + 2.69 | 0.99 | 84.52 ± 5.04 | 3n | y = 7.884x − 2.02 | 0.89 | 7.79 ± 0.33 | y = 3.300x + 2.69 | 0.97 | 5.03 ± 0.57 | 3o | y = 7.532x + 3.12 | 0.94 | 1.78 ± 0.05 | y = 5.321x + 3.79 | 0.99 | 1.69 ± 0.04 | BT | y = 4.783x − 2.367 | 0.94 | 34.69 ± 2.15 | y = 2.241x + 0.57 | 0.94 | 94.96 ± 7.29 | TC | y = 2.675x + 0.107 | 0.93 | 67.45 ± 3.6 | y = 2.152x + 0.94 | 0.96 | 77.04 ± 1.96 |
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