Synthesis of N-Methylmorpholinium Derivatives Possessing a 1,3,4-Oxadiazole Core as Feasible Antibacterial Agents against Plant Bacterial Diseases

Table 1

In vitro antibacterial effects of compounds 3a–3o against Xoo and Xac.

Compd.	Xoo			Xac
	Regression equation	R^2	EC50 (μg/mL)	Regression equation	R^2	EC50 (μg/mL)
3a	y = 7.381x − 3.59	0.88	14.56 ± 1.03	y = 1.281x + 3.60	0.97	12.41 ± 0.57
3b	y = 1.632x + 3.78	0.95	5.65 ± 0.88	y = 1.300x + 4.38	0.95	2.99 ± 0.26
3c	y = 6.824x + 3.43	0.84	1.70 ± 0.01	y = 4.201x + 4.13	0.87	1.61 ± 0.06
3d	y = 4.435x + 1.40	0.84	6.50 ± 0.30	y = 1.183x + 4.01	0.98	6.98 ± 1.33
3e	y = 4.424x + 3.77	0.91	1.90 ± 0.10	y = 2.481x + 3.87	0.92	2.86 ± 0.17
3f	y = 7.873x + 3.00	0.98	1.80 ± 0.14	y = 2.881x + 4.40	0.95	1.61 ± 0.10
3g	y = 13.262x − 8.20	0.98	9.90 ± 0.18	y = 2.972x + 2.26	0.92	8.36 ± 0.44
3h	y = 9.761x + 0.11	0.97	3.17 ± 0.42	y = 3.600x + 3.09	0.95	3.39 ± 0.14
3i	y = 10.972x + 0.12	0.95	2.80 ± 0.24	y = 6.021x + 5.26	0.83	0.90 ± 0.01
3j	y = 2.661x + 2.47	0.87	8.90 ± 0.81	y = 4.173x + 0.47	0.92	12.24 ± 0.42
3k	y = 4.711x + 2.58	0.95	3.27 ± 0.34	y = 0.731x + 4.39	0.99	6.92 ± 0.93
3l	y = 6.352x + 4.07	0.96	1.40 ± 0.06	y = 6.572x + 3.94	0.97	1.45 ± 0.04
3m	y = 2.632x + 0.62	0.94	45.98 ± 4.70	y = 1.200x + 2.69	0.99	84.52 ± 5.04
3n	y = 7.884x − 2.02	0.89	7.79 ± 0.33	y = 3.300x + 2.69	0.97	5.03 ± 0.57
3o	y = 7.532x + 3.12	0.94	1.78 ± 0.05	y = 5.321x + 3.79	0.99	1.69 ± 0.04
BT	y = 4.783x − 2.367	0.94	34.69 ± 2.15	y = 2.241x + 0.57	0.94	94.96 ± 7.29
TC	y = 2.675x + 0.107	0.93	67.45 ± 3.6	y = 2.152x + 0.94	0.96	77.04 ± 1.96