Research Article

Hepatoprotection and Phytochemistry of the Vietnamese Herbs Cleome chelidonii and Cleome viscosa Stems

Table 1

The cytotoxicity using HepG2 of extracts of Cleome chelidonii.

OD570 ± SEMPercentage of control (%)
Concentration (μg/mL)CCSHControlCCSEControlCCSMControlCCSHCCSECCSM

After 24 h of treatment
1000.281 ± 0.0100.243 ± 0.0020.269 ± 0.0020.213 ± 0.0030.293 ± 0.0090.313 ± 0.012108.3126.493.7
500.281 ± 0.0080.260 ± 0.0060.266 ± 0.0040.216 ± 0.0070.300 ± 0.010107.0123.695.9
250.270 ± 0.0070.263 ± 0.0080.250 ± 0.0050.231 ± 0.0070.281 ± 0.010102.7108.190.0
DOX 100.149 ± 0.0050.149 ± 0.0050.164 ± 0.00656.759.352.5

After 48 h of treatment
1000.402 ± 0.0100.282 ± 0.0050.420 ± 0.0030.265 ± 0.0090.313 ± 0.0070.326 ± 0.005117.8158.495.9
500.367 ± 0.0040.341 ± 0.0110.396 ± 0.0060.319 ± 0.0040.323 ± 0.01097.1124.398.9
250.367 ± 0.0050.378 ± 0.0110.360 ± 0.0070.359 ± 0.0050.314 ± 0.00797.2100.396.3
DOX 100.113 ± 0.0040.112 ± 0.0030.091 ± 0.00229.931.227.9

After 72 h of treatment
1000.429 ± 0.0120.315 ± 0.0100.441 ± 0.0140.289 ± 0.0120.403 ± 0.0140.339 ± 0.022121.4152.2118.6
500.394 ± 0.0160.353 ± 0.0090.420 ± 0.0120.329 ± 0.0090.410 ± 0.01798.7127.6120.8
250.388 ± 0.0110.399 ± 0.0060.441 ± 0.0170.393 ± 0.0060.406 ± 0.01097.3112.3119.5
DOX 100.071 ± 0.0020.076 ± 0.0010.068 ± 0.00117.819.320.0