Research Article

Hepatoprotection and Phytochemistry of the Vietnamese Herbs Cleome chelidonii and Cleome viscosa Stems

Table 2

The cytotoxicity using HepG2 of extracts of Cleome viscosa.

OD570 ± SEMPercentage of control (%)
Concentration (μg/mL)CVSHControlCVSEControlCVSMControlCVSHCVSECVSM

After 24 h of treatment
1000.232 ± 0.0140.234 ± 0.0040.274 ± 0.0090.244 ± 0.0090.267 ± 0.0080.230 ± 0.00792.9112.2116.3
500.254 ± 0.0080.250 ± 0.0080.256 ± 0.0070.242 ± 0.0050.265 ± 0.01198.0105.7115.5
250.260 ± 0.0040.259 ± 0.0120.258 ± 0.0100.266 ± 0.0040.250 ± 0.013100.396.7108.7
DOX 100.157 ± 0.0040.186 ± 0.0060.164 ± 0.00660.569.851.7

After 48 h of treatment
1000.314 ± 0.0090.268 ± 0.0080.274 ± 0.0090.271 ± 0.0120.322 ± 0.0080.312 ± 0.00797.2101.4103.4
500.308 ± 0.0110.306 ± 0.0110.304 ± 0.0090.291 ± 0.0080.311 ± 0.00285.4104.699.8
250.329 ± 0.0080.365 ± 0.0030.297 ± 0.0080.332 ± 0.0040.311 ± 0.00591.089.499.8
DOX 100.129 ± 0.0030.130 ± 0.0060.114 ± 0.00335.739.336.4

After 72 h of treatment
1000.405 ± 0.0140.299 ± 0.0190.279 ± 0.0130.303 ± 0.0140.365 ± 0.0070.325 ± 0.008121.792.2112.3
500.368 ± 0.0050.333 ± 0.0110.374 ± 0.0280.345 ± 0.0120.372 ± 0.01397.2108.3114.5
250.368 ± 0.0150.378 ± 0.0080.356 ± 0.0200.390 ± 0.0170.381 ± 0.01497.391.4117.2
DOX 100.073 ± 0.0020.075 ± 0.0010.066 ± 0.00119.219.320.3