Synthesis and Molecular Docking of Some Grossgemin Amino Derivatives as Tubulin Inhibitors Targeting Colchicine Binding Site

<div>The pharmacophoric model of CBSIs with two planes: plane A (red) consists of points A1, D1, H1 and R1; plane B (blue) consists of points A2, A3, and H2 (based on Ref. [<a href="/journals/jchem/2021/5586515/#B33">33</a>, <a href="/journals/jchem/2021/5586515/#B34">34</a>]).</div>

Journal of Chemistry

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Figure 3

Figure 3: Synthesis and Molecular Docking of Some Grossgemin Amino Derivatives as Tubulin Inhibitors Targeting Colchicine Binding Site 