Synthesis and Molecular Docking of Some Grossgemin Amino Derivatives as Tubulin Inhibitors Targeting Colchicine Binding Site

Figure 7

(a) 3D structure of colchicine, docked into the colchicine binding site. (b) Mapping surface showing colchicine, occupying the active pocket of colchicine binding site. (c) 2D structure of colchicine, docked into the colchicine binding site. (d) 3D alignment of colchicine (carbon atoms in turquoise) with the DAMA-colchicine (carbon atoms in green).

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