Synthesis and Molecular Docking of Some Grossgemin Amino Derivatives as Tubulin Inhibitors Targeting Colchicine Binding Site

Table 1

The docking scores of the synthesized compounds, colchicine, and colchicine against tubulin receptor.

Comp.	Binding free energy (kcal/mol)	Comp.	Binding free energy (kcal/mol)
1	−18.00	5	−29.34
2	−24.57	6	−26.38
3	−25.05	7	−26.86
4	−32.16	Colchicine	−26.13