Synthesis, Antibacterial, Antioxidant, and Molecular Modeling Studies of Novel [2,3′-Biquinoline]-4-Carboxylic Acid and Quinoline-3-Carbaldehyde Analogs

Table 2

The % inhibition of the synthetic compounds.

Compounds	Concentrations in μg/mL					IC50 (μg/mL)
	25	20	15	10	5
4	29.22 ± 1.37	27.38 ± 0.49	26.67 ± 1.07	24.96 ± 0.49	21.98 ± 2.45	85.4
7	58.78 ± 2.53	52.20 ± 0.65	50.64 ± 186	40.36 ± 1.59	34.75 ± 2.46	17.2
9	83.26 ± 1.72	80.85 ± 0.43	79.86 ± 0.99	77.72 ± 1.05	52.27 ± 2.98	1.25
10	17.64 ± 1.31	14.61 ± 0.25	13.48 ± 0.25	10.35 ± 0.25	2.55 ± 0.0	75.1
12	52.48 ± 1.23	51.34 ± 0.49	27.52 ± 1.72	25.81 ± 0.49	7.81 ± 0.25	22.40
15	25.25 ± 0.88	27.23 ± 0.0	24.82 ± 0.25	11.20 ± 0.25	4.40 ± 0.24	42.75
17	33.48 ± 1.48	24.54 ± 0.88	24.68 ± 0.43	22.13 ± 1.86	9.36 ± 1.27	41.8
20	89.50 ± 0.65	84.78 ± 0.37	80.30 ± 0.97	64.52 ± 1.12	53.41 ± 0.87	1.75
21	45.53 ± 1.28	44.40 ± 0.24	31.34 ± 0.98	29.32 ± 1.08	6.52 ± 0.25	25.0
Ascorbic acid	95.83 ± 1.19	86.46 ± 0.54	76.60 ± 0.53	64.40 ± 0.62	48.91 ± 0.49	4.5