1,5-Dichloroethanoanthracene Derivatives As Antidepressant Maprotiline Analogs: Synthesis, DFT Computational Calculations, and Molecular Docking

<div>Binding modes of (a) compound 1, (b) compound 2, (c) compound 5, (d) compound 6, (e) standard drug maprotiline, and (f) the native ligand, desipramine at the central binding site of Leu T.</div>

Journal of Chemistry

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Figure 8

Figure 8: 1,5-Dichloroethanoanthracene Derivatives As Antidepressant Maprotiline Analogs: Synthesis, DFT Computational Calculations, and Molecular Docking 

Figure 8 | 1,5-Dichloroethanoanthracene Derivatives As Antidepressant Maprotiline Analogs: Synthesis, DFT Computational Calculations, and Molecular Docking 