Evaluation of 3,5-Diphenyl-2-Pyrazolines for Antimitotic Activity by Inhibition of Tubulin Polymerization

Figure 3

(a) Clonogenic long-term survival assay of 3,5-diphenyl-2-pyrazoline derivatives against HCT116 human colon cancer cells at different concentrations (0, 1, 5, 10, and 20 μM) and (b) of derivatives 4, 6, 9, 10, 11, and 12 at lower concentrations (0, 0.1, 0.5, 1, and 5 μM).