Research Article

Coordination Chemistry, Antibacterial Screening, and In Silico ADME Study of Mononuclear NiII and CuII Complexes of Asymmetric Schiff Base of Streptomycin and Aniline

Table 6

Results of physicochemical properties obtained from SwissADME web server.

Physicochemical properties

FormulaC21H39N7O12C27H44N8O11
Molecular weight581.57 g/mol656.69 g/mol
Num. rotatable bonds1112
Num. H-bond acceptors1515
Num. H-bond donors1414
Molar refractivity130.43158.96
TPSA331.43 Å2326.72 Å2
Lipophilicity (Log Po/w)−5.87−4.34
Water solubilityHighly solubleHighly soluble

The first column is the data of streptomycin, and the second is of Schiff base.