Antioxidant and Anti-Inflammatory Activities of Phytochemicals from Ruellia tuberosa

Figure 3

Effects on the secretion of IL-6 and IL-10 of the (a, b) extract and (c, d) compounds 6–8 in LPS-induced RAW 264.7 macrophages. Cells were pretreated for 2 h with indicated concentrations (5, 10, 20, 30, and 40 μg/mL) and then stimulated with LPS (1 μg/mL) for another 24 h. Data are expressed as mean ± S.D. of three independent experiments.  < 0.05 versus the LPS group; # < 0.05 versus the positive group. RTH: (n)-hexane fraction; RTEA: ethyl acetate fraction; RTM: methanol fraction; RTE: crude ethanol extract.

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