Research Article

An In Silico Study of the Interactions of Alkaloids from Cryptolepis sanguinolenta with Plasmodium falciparum Dihydrofolate Reductase and Dihydroorotate Dehydrogenase

Figure 6

Interactions of some alkaloids with dm-PfDHFR: 3D (left) and 2D (right) views of interactions of (a) cryptolepinone and (b) hydroxycryptolepine with residues in the binding region of double mutant PfDHFR (1J3J). Description of interactions is provided under 2D images.
(a)
(b)