Manganese Schiff Base Complexes, Crystallographic Studies, Anticancer Activities, and Molecular Docking

Table 12

Anticancer effects of Schiff base ligand and its metal complexes of % cell inhibition at different concentrations against MCF-7 breast cancer cell line.

Samples	% cell inhibition	Surviving fraction (MCF-7)					IC50 (μg/ml)
		0.0	5.0	12.5	25	50
L	67	1	0.95	0.85	0.61	0.23	31
[Cr(L) (H2O)2Cl]Cl3·2H2O	67	1	0.95	0.71	0.46	0.25	23
[Mn(L) (H2O)Cl]Cl·3H2O	70	1	0.8	0.75	0.38	0.28	21