Manganese Schiff Base Complexes, Crystallographic Studies, Anticancer Activities, and Molecular Docking

Table 7

Half-maximal inhibitory concentration (μmol/l) results for the parent E-N’-(1-(pyrindin-2-yl)ethylidene) nicotinohydrazide ligand and four metal complexes against three anticancer cell lines, namely, human lung cancer (A549), human gastric cancer cell line (BGC823), and human esophageal cancer (ECA-109) cell lines.

Compound	EC50 (μmol/l)
	A549	BGC823	ECA-109
Ligand	156.5	196.8	165.1
[Cd(penh)2]	13.5	15.6	11.9
[Co(penh)2]	8.1	11.8	10.3
[Cu(penh)2]	7.3	9.7	6.5
[Mn(penh)2]	12.2	18.3	9.6