Comparative Study of Antioxidant, Antidiabetic, Cytotoxic Potentials, and Phytochemicals of Fenugreek (Trigonella foenum-graecum) and Ginger (Zingiber officinale)

Table 4

Different extracts and biological efficacies of Trigonella foenum-graecum leaf.

Sample	ME	EE	NHE	AE	Control
Antioxidant contents and activity
TFC	2.38 ± 0.26	1.88 ± 0.31	1.51 ± 0.58	2.93 ± 0.09	—
TPC	6.23 ± 0.76	6.18 ± 0.06	5.75 ± 0.86	5.74 ± 0.81	—
DPPH	32.56	45.78	38.14	50.27	90
Antidiabetic activity—percentage inhibition
Glycation	29∗	23	16	20	53
Alpha-amylase	24.95	17.93	11.30	9.43	48.20
Antiamnesic activity
AChE inhibition	14.08	8.37	4.62	10.37	59.51

Data expressed as mean ± SD or percentage of triplicate measurements. Significant at . ME: methanol extract; EE: ethanol extract; NHE: n-hexane extract; AE: aqueous extract. TPC: total phenolic contents expressed as g gallic acid equivalents/100 g dry weight; TFC: total flavonoid contents expressed as g catechin equivalents/100 g dry weight; DPPH: 2,2-diphenyl l-picrylhydrazyl free radical scavenging potential expressed as percentage. Positive controls: BHT; butylated hydroxytoluene (antioxidant activity), metformin (antiglycation assay), physostigmine (AChE inhibitory assay), glucobay (alpha-amylase inhibitory assay), and acarbose (alpha-glucosidase).