In Silico, SwissADME, and DFT Studies of Newly Synthesized Oxindole Derivatives Followed by Antioxidant Studies

Table 2

The physicochemical property of oxindole (C-1 and C-2) derivatives calculated with the SwissADME database.

Ligands	Molecular formula	MW (g/mol)	nHA	nAHA	F.Csp^3	nRB	nHBA	nHBD	MR	TPSA (A^2)
C-1	C15H8Cl3NO	324.59	20	12	0.00	1	1	1	87.17	29.10
C-2	C15H8Cl3NO	324.59	20	12	0.00	1	1	1	87.17	29.10

MW: molecular weight; nHA: no. of heavy atom; nAHA: no. of arom. heavy atom; F.Csp³: no. of sp³ hybridized carbon out of total carbon count; nRB: no. of rotatable bonds; nHBA: no. of H-bond acceptors; nHBD: no. of H-bond donors, MR: molar refractivity; TPSA: topological polar surface area.