Research Article

In Silico, SwissADME, and DFT Studies of Newly Synthesized Oxindole Derivatives Followed by Antioxidant Studies

Table 3

The characteristics of lipophilicity and water solubility of oxindoles (C-1 and C-2).

LigandsLipophilicityWater solubility
Consensus Log Po/wLog S (ESOL)Solubility classLog S (Ali)Solubility classLog S (SILICOS-IT)Solubility class

C-14.33−5.24Moderately soluble−5.12Moderately soluble−7.26Poorly soluble
C-24.34−5.24Moderately soluble−5.12Moderately soluble−7.26Poorly soluble