In Silico, SwissADME, and DFT Studies of Newly Synthesized Oxindole Derivatives Followed by Antioxidant Studies

Table 4

The bioavailability scores and pharmacokinetics of oxindole (C1 and C2) derivatives calculated with SwissADME database.

Ligands	GI abs	Bioavail. Score	BBB per	P-gp substrate	CYP1A2 inh	CYP2C 19 inh	CYP2C9 inh	CYP2D6 inh	CYP3A4 inh
C-1	High	0.55	Yes	No	Yes	Yes	Yes	No	No
C-2	High	0.55	Yes	No	Yes	Yes	Yes	No	No