In Silico, SwissADME, and DFT Studies of Newly Synthesized Oxindole Derivatives Followed by Antioxidant Studies

Table 5

Drug-likeness scores and medicinal chemistry properties of oxindoles (C-1 and C-2).

Ligands	Drug-likeness rules					Medicinal chemistry
	Lipinski	Ghose	Veber	Egan	Muegge	PAINS	Brenk	Lead likeness	Synthetic accessibility
C-1	Yes	Yes	Yes	Yes	Yes	0 alert	2 alerts: michael_acceptor-, stilbene	No; 1 violation: XLOGP3 > 3.5	2.52
C-2	Yes	Yes	Yes	Yes	Yes	0 alert	2 alerts: michael_acceptor_1, stilbene	No; 1 violation: XLOGP3 > 3.5	2.55