In Silico, SwissADME, and DFT Studies of Newly Synthesized Oxindole Derivatives Followed by Antioxidant Studies

Table 8

Results of compounds (C-1 and C-2) for DPPH scavenging activity.

Compounds	Concentrations (μM)	Findings	% Inhibition	IC50 (μM)
Control		0.706 ± 0.02845
Compound 1	1000	0.066 ± 0.00115	91	37.390
	500	0.09833 ± 0.00203	86
	250	0.151 ± 0.00524	79
	125	0.24067 ± 0.01784	66
	62.5	0.28533 ± 0.01419	60
Compound 2	1000	0.10 ± 0.00651	86	34.676
	500	0.13466 ± 0.02577	81
	250	0.191 ± 0.00681	73
	125	0.25067 ± 0.01995	64
	62.5	0.29 ± 0.05105	59
Standard	1000	0.05367 ± 0.00145	92	29.363
	500	0.07467 ± 0.01586	89
	250	0.143 ± 0.01539	80
	125	0.207 ± 0.00436	71
	62.5	0.263 ± 0.00961	63

Inhibition percentages (%) and IC₅₀ values (mean ± SEM of n = 3) are used to present the results.  < 0.05 significant;  < 0.01 significant.