In Silico, SwissADME, and DFT Studies of Newly Synthesized Oxindole Derivatives Followed by Antioxidant Studies

Table 9

Results of compounds (C-1 and C-2) for ABTS scavenging activity.

Compounds	Concentrations (μM)	Findings	% Inhibition	IC50 (μM)
Control		0.65333 ± 0.01453
Compound 1	1000	0.08167 ± 0.00203	88	25.381
	500	0.102 ± 0.00751	84
	250	0.17133 ± 0.0109	74
	125	0.20833 ± 0.00924	68
	62.5	0.24133 ± 0.00328	63
Compound 2	1000	0.09533 ± 0.00176	85	33.706
	500	0.14 ± 0.02183	79
	250	0.198 ± 0.0168	70
	125	0.23267 ± 0.00639	64
	62.5	0.267 ± 0.01332	59
Standard	1000	0.048 ± 0.00208	93	26.522
	500	0.0692 ± 0.0283	90
	250	0.129 ± 0.00231	82
	125	0.14313 ± 0.09187	78
	62.5	0.23467 ± 0.00666	64

Inhibition percentages (%) and IC₅₀ values (mean ± SEM of n = 3) are used to present the results.  < 0.05;  < 0.01.