Research Article
Development of Modified-Release Diclofenac Sodium Capsules Using Blends of Pectin-Clay Multiparticulate Hybrid Systems as Release Retardants
Table 1
Working formula for diclofenac pectin-clay capsules.
| Ingredients (mg) | F1 | F2 | F3 | A1 | A2 | A3 | C1 |
| Diclofenac sodium | 50 | 50 | 50 | 50 | 50 | 50 | 50 | CPH pectin | 50 | 50 | 50 | 50 | 50 | 50 | 50 | Bentonite | 10 | 25 | 50 | 0 | 0 | 0 | 0 | Talc | 0 | 0 | 0 | 10 | 25 | 50 | 0 | Dicalcium phosphate | 90 | 75 | 50 | 90 | 75 | 50 | 100 | Distilled water | q.s | q.s | q.s | q.s | q.s | q.s | q.s |
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