Development of Modified-Release Diclofenac Sodium Capsules Using Blends of Pectin-Clay Multiparticulate Hybrid Systems as Release Retardants

Table 2

Flow properties of the CPH pectin-based diclofenac multiparticulate matrix.

Parameters	DPT granules	DPB granules
Angle of repose (°)	29.40 ± 0.50	27.53 ± 0.85
Bulk density (g/mL)	0.67 ± 0.10	0.73 ± 0.00
Tapped density (g/mL)	0.71 ± 0.00	0.77 ± 0.01
Hausner ratio	1.06 ± 0.05	1.05 ± 0.02
Carr’s index (%)	5.63 ± 0.20	5.19 ± 0.01
Flow	Excellent	Excellent