Research Article
Development of Modified-Release Diclofenac Sodium Capsules Using Blends of Pectin-Clay Multiparticulate Hybrid Systems as Release Retardants
Table 2
Flow properties of the CPH pectin-based diclofenac multiparticulate matrix.
| Parameters | DPT granules | DPB granules |
| Angle of repose (°) | 29.40 ± 0.50 | 27.53 ± 0.85 | Bulk density (g/mL) | 0.67 ± 0.10 | 0.73 ± 0.00 | Tapped density (g/mL) | 0.71 ± 0.00 | 0.77 ± 0.01 | Hausner ratio | 1.06 ± 0.05 | 1.05 ± 0.02 | Carr’s index (%) | 5.63 ± 0.20 | 5.19 ± 0.01 | Flow | Excellent | Excellent |
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