Research Article
Development of Modified-Release Diclofenac Sodium Capsules Using Blends of Pectin-Clay Multiparticulate Hybrid Systems as Release Retardants
Table 3
Elemental content of pectin-clay diclofenac multiparticulate composites.
| | Elements | Content in the pectin-bentonite diclofenac matrix (mass %) | Content in the pectin-talc diclofenac matrix (mass %) |
| | Mg | 0.74 ± 0.04 | 9.70 ± 0.01 | | Al | 1.60 ± 0.05 | 0.91 ± 0.02 | | Si | 4.10 ± 0.11 | 14.10 ± 0.07 | | P | 2.75 ± 0.09 | 21.60 ± 0.07 | | S | 0.22 ± 0.01 | 1.12 ± 0.01 | | K | 1.57 ± 0.06 | 4.16 ± 0.01 | | Ca | 73.40 ± 0.49 | 37.30 ± 0.14 | | Cr | − | 0.003 ± 7.07 | | Mn | 0.13 ± 0.00 | 0.04 ± 0.00 | | Fe | 9.34 ± 0.02 | 0.93 ± 0.01 | | Co | 0.04 ± 0.00 | 0.01 ± 0.00 | | Ni | 0.01 ± 0.00 | 0.004 ± 0.00 | | Cu | 0.03 ± 0.00 | 0.01 ± 0.00 | | Zn | − | 0.02 ± 0.00 | | Na | 0.0008 ± 0.11 | 10.06 ± 0.08 |
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(−): absent. Values presented as the mean ± SEM (n = 3).
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