Molecular Design and In-Silico Analysis of Trisubstituted Benzimidazole Derivatives as Ftsz Inhibitor

Table 2

Biological activity of top 7 compounds.

Code	Activity (Pa > Pi)	Pa	Pi
A6	Antibacterial/antimitotic	—	—
A10	Antibacterial/antimitotic	0.218	0.047
A11	Antibacterial/antimitotic	0.222	0.046
A15	Antibacterial/antimitotic	0.179	0.069
A19	Antibacterial/antimitotic	0.195	0.060
A20	Antibacterial/antimitotic	0.222	0.046

Pa = probability “to be active”; Pi = probability “to be inactive”.