Novel Xanthene-1,8-dione Derivatives Containing the Benzylic Ether Tail as Potent Cytotoxic Agents: Design, Synthesis, In Vitro, and In Silico Studies

Table 3

The IC₅₀ values of the xanthene-1,8-diones in MTT assay against A549 cell.

Complex	IC50 (µM)
4a	34.59 ± 1.84
4b	>100
4c	>100
4d	>100
4e	>100
4f	>100
4g	>100
4h	>100
4i	>100
4j	>100
4k	>100
4l	>100
4m	>100
4n	>100
4o	>100
4p	>100
4q	>100
Cis-platin	20.86 ± 4.25