Review Article

A Review on Bioactive Phytochemical Constituents and Pharmacological Activities of Aegiceras corniculatum: A Pharmaceutically Important Mangrove Plant

Table 1

Phytoconstituents from different parts of A. corniculatum.

Parts usedChemicalReference

Leaves3-O-[α-L-Rhamnopyranosyl-(1 ⟶ 2)-α-L-rhamnopyranosyl- (1 ⟶ 2)-β-D-galactopyranosyl-(1 ⟶ 3)-β-D-glucopyranosyl- (1 ⟶ 2)-β-D-(6′-O-methyl)glucuronopyranosyl]-13β, 28- epoxy-3β, 16α-dihydroxy-olean; (3β, 16α, 20α)-3, 16, 28-trihydroxyolean-12-en-29-oic acid 3-{O-β-D-glucopyranosyl (1 ⟶ 2)-O-[β-D-glucopyranosyl (1 ⟶ 4)]-α-L-arabinopyranoside}; aegicoroside A; sakurasosaponin[14]
2-O-Acetyl-5-O-methylembelin; delphinidin-3-O-beta-glucopyranoside; rutin; rhodojaponin I; isoschaftoside; kaempferol-3-rhamnoside-4″-rhamnoside-7-rhamnoside; isobutyryl-coenzyme A; rebaudioside C; aegicerin saponin; protoprimulagenin saponin; sakurasosaponin; ganoderic acid H; 25S-Inokosterone; decumbesterone A; fructose 1,6-diphosphate[10]
Arachidic acid; heneicosanoic acid; myristoleic acid; linolelaidic acid; linoleic acid and cis-4,7,11,14,17-eicosapentaenoic acid[18]
Aegicoroside A; sakurasosaponin; sakurasosaponin methyl ester; (3β, 16α, 20α)-3, 16, 28-trihydroxyolean-12-en-29-oic acid 3-{O-β-D-glucopyranosyl (1 ⟶ 2)-O-[β-D-glucopyranosyl (1 ⟶ 4)]-α-L-arabinopyranoside}; rutin; nicotiflorin[19]
Oleanolic acid β-D-glucopyranosyl ester; isoquecitrin; quercitrin; isomyricitrin; hyperoside; myricitroside; astragalin; quercetin-3-D-xy-loside; chondrillasterol; stigmasterol
Palmitic acid; α-linolenic acid; linolenic acid; palmitoleic acid; stearic acid; oleic acid; heptadecanoic acid[20]
4,4′-(Tetramethylenebisoxy) bis (2-nitro-5-methoxybenzoic acid methyl) ester; ethyl 2,2-diethoxyacetate; pentadecan-4-yl cyclopentanecarboxylate; 2-O-(2-methylpropyl) 1-O-pentyl oxalate; N-(4- nitrobenzilidene)-tert-butylamine[21]

BarkAcornine 1; acornine 2[7]
16-alpha-Hydroxy-13,28-epoxyoleanan-3-one; protoprimulagenin; aegicerin; embelinone; syringic acid; gallic acid; isorhamnetin 3-O-a-l-rhamnopyranosyl-(1Y6)-h-d-glucopyranoside[22]
Palmitic acid; α-linolenic acid; linolenic acid; oleic acid; stearic acid[20]

Root/pneumatophoreGallic acid[11]
Methyl cis-5, 8, 11, 14- eicosatrienoic acid; linoleic acid; palmitic acid; lignoceric acid; Cis-10 heptadecanoic acid; stearic acid; oleic acid; palmitoleic acid[20]

Stem and twigs2-Hydroxy5-ethoxy-3-nonyl-1,4-benzoquinone; 5-O-butyl-embelin; 2,5-dihydroxy-6-methyl-3-pentadecyl-1,4-benzoquinone; 2,5-dihydroxy-3-methyl-6-nonyl-1,4-benzoquinone; 2,5-dihydroxy-3-methyl-6-undecyl-1,4-benzoquinone; 2,5-dihydroxy-6-methyl-3-tridecyl-1,4-benzoquinone; 2-hydroxy-5-methoxy-3-nonyl-1,4-benzoquinone; 5-O-methylembelin; 5-O-methyl-rapanone; 5-O-ethylembelin[23]
Myristic acid; palmitic acid; linolenic acid; cis-11, 14, 17-eicosatrienoic acid and arachidonic acid[18]
2-Methoxy-3-nonylresorcinol; 5-O-ethylembelin; 2-O-acetyl-5-O-methylembelin; 3,7-dihydroxy2,5-diundecylnaphthoquinone; 2,7-dihydroxy-8-methoxy-3,6-diundecyldibenzofuran-1,4-dione; 2,8- dihydroxy-7-methoxy-3,9-diundecyldibenzofuran-1,4-dione; 10-hydroxy-4-O-methyl-2,11-diundecylgomphilactone; 5-O-methylembelin; 3-undecylresorcinol, and 2-dehydroxy-5-O-methylembelin[16]
Sitosterol; protocatechuic acid; vanillic acid; daucterol; schimpefinone; primulagenin A[22]

Unidentified4-Hydroxy-2-methoxybenzamide; 1. 2,5-didehydroxy-6-methylembelin; embelin; 5-O-Ethylembelin; 5-O-Methylembelin; acetylation of 5-O-methylembelin; 4-methoxyresorcinol[24]
Gallocatechin; epigallocatechin; Epigallocatechin-3-O-gallate; Epicatechin-3-O-gallate; epicatechin[25]
Falcarindiol; P-hydroxyphenethyl anisate; phthalic acid; bis (2-ethylhexyl) ester; 1-hentriacontanol; resveratrol; 1,5-dihydroxy-3-methoxy-7-methylanthraquinone; 1,3,5-trihydroxy-7-methylanthraquinone; quercetin; lupeol; benzodiazepines; kaempferol; quercetin; isorhamnetin; aegicerin; aegiceradienol; Genin-A[15]
Vanillic acid; stigmasterol; β-sitosterol; syringic acid; alpha-spinasterol; embelinone; 5-O-methylembelin; protocatechuic acid; 3,28-dihydroxy-16-oxo-12-oleanene; fucosterol[26]