|
| Reported activity | Test model | MIC/IC50/EC50 (μg/ml) | Mechanism | Reference |
|
| Antituberculosis | Against Mtb H37Rv strain | MIC using resazurin microtiter assay, Soxhlet, and maceration techniques, respectively (19.53 μg/ml, 39.06 μg/ml, and 1250 μg/ml) | Through oxidation | [28] |
| Antioxidation | Using DPPH (2,2-diphenyl-1-picrylhydrazyl) | MIC using microwave and SEAF (IC50: 86.31 μg/ml and 165.75 μg/ml) | By scavenging free radicals |
|
| Antioxidant | DPPH radical scavenging activity | Methanolic, water, and ethyl acetate extract of leaf (EC50 value: 55.77, 58.43, and 59.73 µg/ml) | By scavenging free radicals | [32] |
| Methanolic and water extract of bark (EC50: 80.73 and 82.02 µg/ml) |
| Petroleum ether extracts of bark and leaf (EC50; 328 and 201 µg/ml) |
| ABTS + radical scavenging activity | Water extract of leaf and bark (EC50: 84.38 and 87.89 µg/ml) |
| Methanolic extract of leaf and bark (EC50: 89.33 and 102.34 µg/ml) |
| Hydrogen peroxide radical scavenging activity | Petroleum ether extract of leaf and ethyl acetate extract of bark (EC50: 93.59 and 93.44 µg/ml) |
| Water and petroleum ether extract of bark (EC50: 94.19 and 96.09 µg/ml) |
| Water and methanol extract of leaf (EC50: 97.07 and 95.05 µg/ml) |
|
| Antioxidant | DPPH assay | Aqueous ethanol extract of bark and leaves (IC50: 20.49 ± 2.14 µg/mL) | By scavenging free radicals | [33] |
| Anti-inflammation | LOX inhibition assay | Aqueous ethanol extract of bark and leaves (IC50: 23.58 ± 1.75 µg/mL) | Inhibition of lipoxygenase enzyme |
| Anticoagulation | Prothrombin time (PT) determination assay | A. corniculatum bark needed 18.19 ± 0.13 min at highest concentration (800 µg/mL) | N/A |
|
| Neuroprotective | MTT pretreatment method using SK-S-NH neuroblastoma cell lines | Methanol extract of concentration 5 µg/ml showed 70.02% cell viability | Hinders lipid peroxidation, DNA damage, and the production of reactive oxygen species (ROS) | [34] |
|
| Cytotoxicity | On Vero cell lines | Silver nanoparticles using a mangrove extract of Aegiceras corniculatum (IC50 was 18.79 ± 0.9 µg/mL) | N/A | [35] |
|
| Anthelmintic | Using adult earthworms (Pheretima posthuma) | Petroleum ether, chloroform, methanol, and aqueous extract of Aegiceras corniculatum stem are used in 50 and 100 mg/ml concentration | N/A | [36] |
|
| Antidiabetic | Alpha glycosidase enzyme activity inhibition | IC50 of ethyl acetate and water extract of the Aegiceras corniculatum leaves was 40.59 µg/mL and 60.79 µg/mL, respectively | α-Glucosidase inhibition | [37] |
|
