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Journal of Drug Delivery
Volume 2011, Article ID 415621, 9 pages
http://dx.doi.org/10.1155/2011/415621
Research Article

Unveiling Stability Criteria of DNA-Carbon Nanotubes Constructs by Scanning Tunneling Microscopy and Computational Modeling

1Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND 58108-6050, USA
2Los Alamos National Laboratory, Center for Integrated Nanotechnologies, Los Alamos, NM 87545, USA
3NIST Center for Nanoscale Science and Technology, Energy Research Group, Gaithersburg, MD 20899, USA
4Los Alamos National Laboratory, Theoretical Division, Los Alamos, NM 87545, USA

Received 1 November 2010; Accepted 22 January 2011

Academic Editor: Giorgia Pastorin

Copyright © 2011 Svetlana Kilina et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. A. Moses, H. Brem, and R. Langer, “Advancing the field of drug delivery: taking aim at cancer,” Cancer Cell, vol. 4, no. 5, pp. 337–341, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. R. Sinha, G. J. Kim, S. Nie, and D. M. Shin, “Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery,” Molecular Cancer Therapeutics, vol. 5, no. 8, pp. 1909–1917, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Ferrari, “Cancer nanotechnology: opportunities and challenges,” Nature Reviews Cancer, vol. 5, no. 3, pp. 161–171, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Lal, S. E. Clare, and N. J. Halas, “Nanoshell-enabled photothermal cancer therapy: impending clinical impact,” Accounts of Chemical Research, vol. 41, no. 12, pp. 1842–1851, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Kostarelos, A. Bianco, and M. Prato, “Promises, facts and challenges for carbon nanotubes in imaging and therapeutics,” Nature Nanotechnology, vol. 4, no. 10, pp. 627–633, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. Z. Liu, W. Cai, L. He et al., “In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice,” Nature Nanotechnology, vol. 2, no. 1, pp. 47–52, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. C. J. Gannon, P. Cherukuri, B. I. Yakobson et al., “Carbon nanotube-enhanced thermal destruction of cancer cells in a noninvasive radiofrequency field,” Cancer, vol. 110, no. 12, pp. 2654–2665, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. N. W. S. Kam, T. C. Jessop, P. A. Wender, and H. Dai, “Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into mammalian cells,” Journal of the American Chemical Society, vol. 126, no. 22, pp. 6850–6851, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. A. A. Bhirde, V. Patel, J. Gavard et al., “Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery,” ACS Nano, vol. 3, no. 2, pp. 307–316, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. K. König, “Multiphoton microscopy in life sciences,” Journal of Microscopy, vol. 200, no. 2, pp. 83–104, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. N. W. S. Kam, M. O'Connell, J. A. Wisdom, and H. Dai, “Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 33, pp. 11600–11605, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. N. W. S. Kam, Z. Liu, and H. Dai, “Carbon nanotubes as intracellular transporters for proteins and DNA: an investigation of the uptake mechanism and pathway,” Angewandte Chemie International Edition, vol. 45, no. 4, pp. 577–581, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. D. A. Heller, H. Jin, B. M. Martinez et al., “Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes,” Nature Nanotechnology, vol. 4, no. 2, pp. 114–120, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. E. L. Gui, L. J. Li, P. S. Lee et al., “Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors,” Applied Physics Letters, vol. 89, no. 23, Article ID 232104, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Wang, G. Liu, and M. R. Jan, “Ultrasensitive electrical biosensing of proteins and dna: carbon-nanotube derived amplification of the recognition and transduction events,” Journal of the American Chemical Society, vol. 126, no. 10, pp. 3010–3011, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. M. Zheng, A. Jagota, M. S. Strano et al., “Structure-based carbon nanotube sorting by sequence-dependent DNA assembly,” Science, vol. 302, no. 5650, pp. 1545–1548, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Zheng, A. Jagota, E. D. Semke et al., “DNA-assisted dispersion and separation of carbon nanotubes,” Nature Materials, vol. 2, no. 5, pp. 338–342, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. D. A. Yarotski, S. V. Kilina, A. A. Talin et al., “Scanning tunneling microscopy of DNA-Wrapped carbon nanotubes,” Nano Letters, vol. 9, no. 1, pp. 12–17, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Lacerda, H. Ali-Boucetta, M. A. Herrero et al., “Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes,” Nanomedicine, vol. 3, no. 2, pp. 149–161, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. R. Singh, D. Pantarotto, L. Lacerda et al., “Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 9, pp. 3357–3362, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. H. Wang, J. Wang, X. Deng et al., “Biodistribution of carbon single-wall carbon nanotubes in mice,” Journal of Nanoscience and Nanotechnology, vol. 4, no. 8, pp. 1019–1024, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. L. Lacerda, M. A. Herrero, K. Venner, A. Bianco, M. Prato, and K. Kostarelos, “Carbon-nanotube shape and individualization critical for renal excretion,” Small, vol. 4, no. 8, pp. 1130–1132, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. H. Gao and Y. Kong, “Simulation of DNA-nanotube interactions,” Annual Review of Materials Research, vol. 34, pp. 123–150, 2004. View at Publisher · View at Google Scholar · View at Scopus
  24. X. Zhao and J. K. Johnson, “Simulation of adsorption of DNA on carbon nanotubes,” Journal of the American Chemical Society, vol. 129, no. 34, pp. 10438–10445, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. R. R. Johnson, A. T. C. Johnson, and M. L. Klein, “Probing the structure of DNA-carbon nanotube hybrids with molecular dynamics,” Nano Letters, vol. 8, no. 1, pp. 69–75, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. T. Kaneko, T. Okada, and R. Hatakeyama, “DNA encapsulation inside carbon nanotubes using micro electrolyte plasmas,” Contributions to Plasma Physics, vol. 47, no. 1-2, pp. 57–63, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. H. Gao, Y. Kong, D. Cui, and C. S. Ozkan, “Spontaneous insertion of DNA oligonucleotides into carbon nanotubes,” Nano Letters, vol. 3, no. 4, pp. 471–473, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. X. Tu, S. Manohar, A. Jagota, and M. Zheng, “DNA sequence motifs for structure-specific recognition and separation of carbon nanotubes,” Nature, vol. 460, no. 7252, pp. 250–253, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. L. Zhang, X. Tu, K. Welsher, X. Wang, M. Zheng, and H. Dai, “Optical characterizations and electronic devices of nearly pure (10,5) single-walled carbon nanotubes,” Journal of the American Chemical Society, vol. 131, no. 7, pp. 2454–2455, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. K. Kostarelos, L. Lacerda, G. Pastorin et al., “Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type,” Nature Nanotechnology, vol. 2, no. 2, pp. 108–113, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Kilina, S. Tretiak, S. K. Doorn et al., “Cross-polarized excitons in carbon nanotubes,” Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 19, pp. 6797–6802, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. A. Jorio, R. Saito, J. H. Hafner et al., “Structural (n, m) determination of isolated single-wall carbon nanotubes by resonant Raman scattering,” Physical Review Letters, vol. 86, no. 6, pp. 1118–1121, 2001. View at Publisher · View at Google Scholar · View at Scopus
  33. S. Meng, P. Maragakis, C. Papaloukas, and E. Kaxiras, “DNA nucleoside interaction and identification with carbon nanotubes,” Nano Letters, vol. 7, no. 1, pp. 45–50, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. HyperChem Lite v. 2, Hypercube Inc., Gainesville, Fla, USA, 1991.
  35. N. Foloppe and A. D. MacKerell Jr., “All-atom empirical force field for nucleic acids: I. Parameter optimization based on small molecule and condensed phase macromolecular target data,” Journal of Computational Chemistry, vol. 21, no. 2, pp. 86–104, 2000. View at Google Scholar · View at Scopus
  36. A. D. MacKerell Jr. and N. K. Banavali, “All-atom empirical force field for nucleic acids: II. Application to molecular dynamics simulations of DNA and RNA in solution,” Journal of Computational Chemistry, vol. 21, no. 2, pp. 105–120, 2000. View at Google Scholar · View at Scopus
  37. S. N. Kim, Z. Kuang, J. G. Grote, B. L. Farmer, and R. R. Naik, “Enrichment of (6,5) single wall carbon nanotubes using genomic DNA,” Nano Letters, vol. 8, no. 12, pp. 4415–4420, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. S. R. Lustig, A. Jagota, C. Khripin, and M. Zheng, “Theory of structure-based carbon nanotube separations by Ion-exchange chromatography of DNA/CNT hybrids,” Journal of Physical Chemistry B, vol. 109, no. 7, pp. 2559–2566, 2005. View at Publisher · View at Google Scholar · View at Scopus
  39. K. Kostarelos, “The long and short of carbon nanotube toxicity,” Nature Biotechnology, vol. 26, no. 7, pp. 774–776, 2008. View at Publisher · View at Google Scholar · View at Scopus