Review Article

The Effects of C-peptide on Type 1 Diabetic Polyneuropathies and Encephalopathy in the BB/Wor-rat

Figure 3

Longitudinal measurements of thermal hyperalgesia in type 1 BB/Wor-rats without and with C-peptide replacement from onset of diabetes compared to duration- and hyperglycemia-matched type 2 BBZDR/Wor-rats and age-matched control rats. Note more severe hyperalgesia in type 1 as compared to type 2 rats and with partial but significant prevention in C-peptide treated rats [48, 49].
230458.fig.003