Phlorizin Prevents Glomerular Hyperfiltration but not Hypertrophy in Diabetic Rats

Figure 2

Glomerular morphological changes due to one-week diabetes in Fischer rats. Glomerular tuft area significantly increased after one week of diabetes. PAS positive area exhibited no change in one-week diabetics (D) when compared to controls (C). Phlorizin treatment (DPLZ) did not prevent glomerular growth. (4 $\mu$m, paraffin sections, periodic acid-Schiff (PAS) stain, $\times 400$).

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(b)

(c)