Islet Specific Wnt Activation in Human Type II Diabetes
Figure 1
Expression of TCF factors in type II diabetes. TCF7L2 (red in (a)–(d)) and TCF3 (red
in (f)–(i)) are absent from islets of nondiabetic individuals (a), (b), (f), and (g), but are present in islets from
type II diabetics (c), (d), (h), and (i). Islets are identified by insulin (green in (b), (d), (g), and (i)). Quantitation of
TCF7L2 (e) and TCF3 (j) expressions in nondiabetic () and type II () islets: error
bars = mean +/−s.e.m. *. Scale bars = 50 m.
