Research Article

Diabetes Alters Contraction-Induced Mitogen Activated Protein Kinase Activation in the Rat Soleus and Plantaris

Figure 2

Contraction-induced Erk1/2-MAPK phosphorylation is altered with type II diabetes. Plantaris and soleus muscles from lean (LNZ) and obese Zucker (OSXZ) rats were obtained immediately after, 1 and 3 hours after a bout of HFES. Alterations in Erk1 (a),(b) and Erk2 (c),(d)-MAPK phosphorylation with exercise were determined by immunoblotting. An asterisk (*) indicates significant difference ( ) from the control within animal model, and a cross () indicates significant difference ( ) at corresponding time points across animal models.
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38101.fig.002b
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